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Located in the fertile plain of Thessaly in central Greece, modern Trikala is the Homeric Trikka, the birthplace of three of the Argonauts and the birthplace of Asclepius. Ruins of an old sanctuary to the physician-god, an Asklepieion, or healing place, are located between the central square and the church of Saint Nicholas in Trikala; it is the oldest Aesculapium of Greece - a kind of medical centre, from which the worship of Aesculapius gradually spread.
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